Table 2.
Cytotoxic activity of saponins fractions (200 μg/ml) from Z. armatum using MTT assay
| Fractions (200 μg/ml) | Percentage growth inhibition of cancer cells (Mean ± Std. Dev.) | |||
|---|---|---|---|---|
| MCF-7 cells | MDA MB-468 cells | Caco-2 cells | Vehicle Control | |
| Zf.Sa | 79.69*** (±7.45) | 95.00*** (±2.64) | 75.88*** (±8.41) | 3.17 (±5.67) |
| Zl.Sa | 49.08** (±5.21) | 85.33*** (±3.41) | 68.62** (±2.48) | 3.43 (±6.80) |
| Zb.Sa | 9.43 (±3.82) | 94.59*** (±3.00) | 61.82** (±4.07) | 0.20 (±2.34) |
| Actinomycin-D (4 μM) | 62.04** (±1.43) | 62.87** (±5.28) | 65.40** (±4.29) | 1.10 (±1.13) |
In the table statistically (Dunnett’s multiple comparison test) * = Significant (P < 0.05), ** = Highly significant (P < 0.01), *** = Very highly significant (P < 0.001)