Table 5.

Frequencies of TFPI polymorphisms in two populations according to genders

SNP	genotype	Population 1						Population 2
		men			women			men			women
		CAD n (%)	Non-CAD n (%)	P	CAD n (%)	Non-CAD n (%)	P	CAD n (%)	Non-CAD n (%)	P	CAD n (%)	Non-CAD n (%)	P
Rs8176528	GG	634	647	0.281	174	182	0.484	335	332	0.327	128	126	0.913
		512	538		144	156		273	281		107	103
		(80.8)	(83.2)		(82.8)	(85.7)		(81.5)	(84.7)		(83.6)	(81.7)
	AA	33	37		7	9		13	15		5	6
		(5.2)	(5.7)		(4.0)	(5.0)		(3.9)	(4.5)		(3.9)	(4.8)
	GA	89	72		23	17		49	36		16	17
		(14.0)	(11.1)		(13.2)	(9.3)		(14.6)	(10.8)		(12.5)	(13.5)
Rs10153820	GG	634	647	0.838	174	182	0.343	335	332	0.988	128	126	0.782
		306	319		109	101		204	201		81	85
		(48.3)	(49.3)		(62.6)	(55.5)		(60.9)	(60.5)		(63.3)	(67.4)
	AA	41	45		7	11		59	60		22	19
		(6.4)	(7.0)		(4.0)	(6.0)		(17.6)	(18.1)		(17.2)	(15.1)
	GA	287	283		58	70		72	71		25	22
		(45.3)	(43.7)		(33.4)	(38.5)		(21.5)	(21.4)		(19.5)	(17.5)
Rs6434222	TT	634	647	<0.001	174	182	0.003	335	332	<0.001	128	126	0.001
		312	379		121	117		166	214		69	71
		(49.2)	(58.6)		(69.5)	(64.3)		(49.6)	(64.5)		(53.9)	(56.3)
	AA	41	73		7	26		7	41		4	19
		(6.5)	(11.3)		(4.1)	(14.3)		(2.0)	(12.3)		(3.1)	(15.1)
	TA	281	195		46	39		162	77		55	36
		(44.3)	(30.1)		(26.4)	(21.4)		(48.4)	(23.2)		(43.0)	(28.6)
Rs7586970	TT	634	647	0.068	174	182	0.263	335	332	0.056	128	126	0.084
		537	549		144	154		293	289		91	102
		(84.7)	(84.9)		(82.8)	(84.6)		(87.5)	(87.0)		(71.1)	(81.0)
	CC	28	44		8	13		10	21		11	11
		(4.4)	(6.8)		(4.6)	(7.2)		(3.0)	(6.4)		(8.6)	(8.7)
	TC	69	54		22	15		32	22		26	13
		(10.9)	(8.3)		(12.6)	(8.2)		(9.5)	(6.6)		(20.3)	(10.3)

Calculations were performed with comparison of three different genotypes. Values are the number (percentage) of subjects. After stratification analysis based on gender, no significant association was found between genotype distributions and CAD in CAD patients and non-CAD controls