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. 2017 Jul 17;9:54. doi: 10.1186/s13098-017-0255-8

Table 5.

Comparison of the effects of dapagliflozin on metabolic parameters with or without renal dysfunction

Variables Dapagliflozin (n = 14) p value
eGFR ≥ 70
[mL min−1 (1.73 m2)−1]
(n = 6)
eGFR < 70
[mL min−1 (1.73 m2)−1]
(n = 8)
ΔMAGE (mg dL−1) −3.4 ± 24.1 11.4 ± 31.9 0.34
ΔHbA1c (%) 0.3 ± 0.7 0.6 ± 0.4 0.35
ΔBMI (kg m−2) −1.2 ± 0.4 −0.7 ± 1.1 0.31

Values are mean ± SD. p value of eGFR ≥ 70 vs eGFR < 70

eGFR estimated glomerular filtration rate, MAGE mean amplitude of glycemic excursions, BMI body mass index