Table 5.
Comparison of the effects of dapagliflozin on metabolic parameters with or without renal dysfunction
| Variables | Dapagliflozin (n = 14) | p value | |
|---|---|---|---|
| eGFR ≥ 70 [mL min−1 (1.73 m2)−1] (n = 6) |
eGFR < 70 [mL min−1 (1.73 m2)−1] (n = 8) |
||
| ΔMAGE (mg dL−1) | −3.4 ± 24.1 | 11.4 ± 31.9 | 0.34 |
| ΔHbA1c (%) | 0.3 ± 0.7 | 0.6 ± 0.4 | 0.35 |
| ΔBMI (kg m−2) | −1.2 ± 0.4 | −0.7 ± 1.1 | 0.31 |
Values are mean ± SD. p value of eGFR ≥ 70 vs eGFR < 70
eGFR estimated glomerular filtration rate, MAGE mean amplitude of glycemic excursions, BMI body mass index