Figure 7.

Internalization of FITC-DMBT1-Peptide and FITC-DMBT1-Peptide-siRNA Complexes by MCF7 Breast Cancer Cells

(A–E) Confocal microscopy images of MCF7 cells treated with FITC-SRCRP2-11 peptide (A), FITC-SRCRP2-11-Cy3-siRNA complex (B), FITC-SRCRP2-11-R peptide (C), FITC-SRCRP2-11-R-Cy3-siRNA complex (D), and naked Cy3-siRNA (E). Colors indicate the following: red, CellMask Deep Red plasma membrane staining of plasma membranes; blue, DAPI staining of nuclei; green, FITC-peptide; yellow, Cy3-siRNA. Scale bars represent 50 μm.