Table 5. . Crude and adjusted association between DNA methylation and Quetelet index.

Methylation	Quetelet index
	Crude model		Adjusted model†
	β (95% CI)	p-value	β (95% CI)	p-value
HSD11B2	-0.111 (-0.224–0.003)	0.056	-0.060 (-0.148 to -0.029)	0.184
NR3C1	0.011 (-0.029–0.052)	0.581	-0.018 (-0.050–0.014)	0.463
WNT2:
– High	-0.070 (-0.144–0.003)	0.061	-0.093 (-0.150 to -0.036)	0.002**
– Low	0.048 (-0.028–0.124)	0.211	0.045 (-0.010–0.100)	0.107
IGF2:
– Pos.1	0.057 (0.006–0.109)	0.030*	0.038 (-0.002–0.077)	0.064
– Pos.2	0.026 (-0.006–0.057)	0.113	0.018 (-0.007–0.042)	0.157
IL6:
– Pos.1	0.007 (-0.083–0.097)	0.878	-0.008 (-0.076–0.061)	0.828
– Pos.2	0.024 (-0.025–0.072)	0.335	0.007 (-0.030–0.044)	0.720
AHRR:
– Pos.1	0.067 (0.025–0.109)	0.002**	0.036 (0.005–0.067)	0.024*
– Pos.2	0.033 (-0.003–0.069)	0.070	0.019 (-0.007–0.045)	0.152
– Pos.3	0.006 (-0.031–0.042)	0.755	0.015 (-0.012–0.041)	0.267

Methylation level of each gene was modeled as the independent variable associated with Quetelet index as the dependent variable.

^†Adjusted for gestational age, infant gender, birth type, prenatal vitamin use and environmental tobacco smoke during pregnancy.

*p < 0.05; **p < 0.01.

High: High WNT2 methylation group; Low: Low WNT2 methylation group; Pos.1: The first studied CpG site; Pos.2: The second studied CpG site; Pos.3: The third studied CpG site.