Table 5.
5-year cancer-specific survival in percent (number of cases) vs intensity of staining in the tumour bulk, invasive front, and lymph node metastases n (%)
| Intensity of staining | Whole colon | P value1 | Proximal colon | P valu1 | Distal colon and rectum | P value1 | ||
| TLR2 | Tumour bulk | Weak | 14 (63.6) | 0.43 | 4 (66.7) | 0.65 | 9 (60.0) | 0.33 |
| Strong | 71 (74.7) | 29 (74.4) | 42 (75.0) | |||||
| Invasive front | Weak | 14 (73.7) | > 0.9 | 6 (66.7) | 0.68 | 8 (80.0) | 0.71 | |
| Strong | 70 (72.2) | 27 (75.0) | 42 (70.0) | |||||
| Lymph node | Weak | 9 (50.0) | 0.55 | 3 (37.5) | > 0.9 | 6 (60.0) | 0.26 | |
| Strong | 10 (40.0) | 3 (42.9) | 6 (35.3) | |||||
| TLR4 | Tumour bulk | Weak | 25 (65.8) | 0.27 | 7 (63.6) | 0.45 | 18 (66.7) | 0.59 |
| Strong | 60 (75.9) | 26 (76.5) | 33 (75.0) | |||||
| Invasive front | Weak | 17 (63.0) | 0.33 | 5 (45.5) | 0.044 | 12 (75.0) | > 0.9 | |
| Strong | 67 (75.3) | 28 (82.4) | 38 (70.4) | |||||
| Lymph node | Weak | 2 (25.0) | 0.27 | 0 (0.0) | 0.23 | 2 (40.0) | > 0.9 | |
| Strong | 17 (48.6) | 6 (50.0) | 10 (45.5) | |||||
1
χ2 test/Fisher’s exact test. N values vary due to missing samples; One case with multiple tumours excluded from location-based analysis; Weak intensity < 2 and strong intensity ≥ 2.