Table 3.
Risk factors for time to death using multiple Cox regression analysis
| Variable (reference group) | Overall survival | |
|---|---|---|
| Hazard Ratio (95% CI) | P-value | |
| yTa | 0.014 | |
| 1 (0) | 0.2 (0; 2.3) | 0.212 |
| 2 (0) | 0.3 (0.1; 1.5) | 0.158 |
| 3 (0) | 0.5 (0.1; 1.9) | 0.309 |
| 4 (0) | 23.1 (1.8; 302.3) | 0.017 |
| yNa | 0.034 | |
| 1 (0) | 1.5 (0.4; 5.4) | 0.489 |
| 2 (0) | 4.2 (1.4; 12.6) | 0.011 |
| DRMb | 0.871 | |
| DRM Group II ( Group I) | 1.3 (0.3; 5.1) | 0.690 |
| DRM Group III (Group I) | 1.4 (0.4; 4.4) | 0.609 |
Values are shown as median (range) for ordinal and numeric variables and as frequency (percentage) for nominal variables
a
yT, yN = stage as assessed by pathologic examination of the surgical specimen (after CRT and resection)
b
DRM = distal resection margin; Group I, DRM < 8mm; Group II, 8 ≤ DRM ≤ 20 mm; Group III, DRM > 20 mm