Table 2.
IHC IGF1R expression by histological/clinical characteristics and diabetes mellitus
| Variable | IGF1R positive No (%) | IGF1R negative No (%) | P value |
|---|---|---|---|
| All patients | 133 (79.6%) | 34 (20.4%) | |
| Histology | 0.03 | ||
| - NSCC | 78 (74.3%) | 27 (25.7%) | |
| - SCC | 55 (88.7%) | 7 (11.3%) | |
| Sex | 0.17 | ||
| - Male | 98 (82.4%) | 21 (17.6%) | |
| - Female | 35 (72.9%) | 13 (27.1%) | |
| Smoking status | 0.77 | ||
| - Current/former smoker | 116 (80.0%) | 29 (20.0%) | |
| - Never smoker | 17 (77.3%) | 5 (22.7%) | |
| ECOG - PS | 0.97 | ||
| - 0–1 | 121 (79.6%) | 31 (20.4%) | |
| - ≥ 2 | 12 (80.0%) | 3 (20.0%) | |
| Diabetes mellitus type 2 | 0.84 | ||
| - No | 119 (79.9%) | 30 (20.1%) | |
| - Yes | 14 (77.8%) | 4 (22.2%) |
ECOG-PS = Eastern Cooperative Oncology Group performance status; IGF1R = insulin-like growth factor-1 receptor; NSCC = non-squamous cell carcinoma; SCC = squamous cell carcinoma