Table 4.
Multivariate logistic regression analysis for lymphopenia of grade 3 or higher
| Variable | OR | 95% CI | p-value |
|---|---|---|---|
| Body A V5 (per 1 × 103 mL increase) | 1.58 | 1.03–2.42 | 0.036 |
| Number of fractions (per 1-fraction increase) | 1.26 | 1.03–1.53 | 0.027 |
| Splenic irradiation (yes vs. no) a | 5.12 | 0.74–35.28 | 0.098 |
| Body A V10 (per 1 × 103 mL increase) | 1.68 | 1.04–2.70 | 0.034 |
| Number of fractions (per 1-fraction increase) | 1.26 | 1.03–1.55 | 0.026 |
| Splenic irradiation (yes vs. no) a | 5.25 | 0.77–35.76 | 0.090 |
| Body B V5 (per 1 × 103 mL increase) | 1.63 | 1.03–2.57 | 0.038 |
| Number of fractions (per 1-fraction increase) | 1.25 | 1.03–1.53 | 0.028 |
| Splenic irradiation (yes vs. no) a | 5.46 | 0.79–37.53 | 0.085 |
| Body B V10 (per 1 × 103 mL increase) | 1.72 | 1.04–2.87 | 0.036 |
| Number of fractions (per 1-fraction increase) | 1.26 | 1.03–1.55 | 0.027 |
| Splenic irradiation (yes vs. no) a | 5.59 | 0.82–37.99 | 0.078 |
CI = confidence interval; OR = odds ratio
a
Yes, if any part of the spleen was covered by the 5 Gy idodose line; Factors with p < 0.05 by univariate analysis (number of fractions and splenic irradiation) were taken into account to test the indep