Table 1b.
Demographic and clinical characteristics of the TBSS groups.
| Characteristic | T2DM N = 13 |
Obese N = 13 |
Controls N = 20 |
F or Fisher's exact test |
p |
|---|---|---|---|---|---|
| Age | 16.00 ± 1.6 | 15.0 ± 1.9 | 16.1 ± 1.9 | 1.34 | 0.27 |
| Sex (female, n, %) | 12 (100%) | 10 (77%) | 14 (70%) | ||
| Ethnicity (n) | |||||
| White | 5 | 8 | 10 | 7.03 | 0.54 |
| Asian | 7 | 3 | 7 | ||
| Black | 0 | 1 | 0 | ||
| Other | 0 | 1 | 3 | ||
| SD-BMI ± sd | 2.01 ± 1.51 n = 13 |
3.11 ± 0.65 n = 13 |
0.32 ± 0.98 n = 20 |
27.54 | < 0.0001 |
| Fasting blood glucose (mmol/l) ± sd | 8.87 ± 3.87 n = 9 |
4.95 ± 0.56 n = 13 |
4.78 ± 0.49 n = 19 |
16.91 | < 0.0001 |
| Fasting insulin (pmol/l) ± sd | 227.5 ± 176.0 n = 7 |
178.2 ± 1.48.5 n = 13 |
72.2 ± 70.1 n = 18 |
5.08 | 0.012 |
| HbA1c (%) ± sd (mmol/mol) |
7.80 ± 1.97 (61.7) n = 12 |
5.55 ± 0.39 (37.2) n = 13 |
5.29 ± 0.33 (34.3) n = 16 |
20.05 | < 0.0001 |
| HOMA-IR ± sd | 102.2 ± 120.2 n = 5 |
41.5 ± 39.8 n = 13 |
15.4 ± 15.2 n = 18 |
6.11 | 0.006 |
| c-peptide (pmol/l) ± sd | 1265.86 ± 886.53 n = 7 |
1296.67 ± 525.51 n = 12 |
747.28 ± 264.98 n = 18 |
5.09 | 0.012 |
| OGTT (mol/l) ± sd | NA | 6.79 ± 1.77 | 5.38 ± 0.94 | 9.01 | < 0.005 |
| Duration of diabetes (months) ± sd | 30.8 ± 23.0 | NA | NA | ||
| Diabetes treatment (n) | |||||
| Metformin | 5 | 1 | NA | ||
| Metformin + gliclazide | 1 | 0 | |||
| Metformin + insulin | 2 | NA | NA | ||
| Metformin + gliclazide + insulin | 1 | NA | NA | ||
| GLP-1 | 1 | 0 | NA |
Values are means ± SD; T2DM = type 2 diabetes; NA = not applicable.