Table 1.
Cell surface molecule expression by freshly isolated CD31+ and CD31- ADASC and by cultured CD31- cells at passage 4
| CD | Name or function | CD31+ uncultured | CD31- uncultured | Passage 4 |
|---|---|---|---|---|
| Endothelium related molecules | ||||
| CD62E | E-selectin | — | — | — |
| CD62P | P-selectin | +/- | — | — |
| CD63 | LAMP-3 | + | +/- | +/- |
| CD105 | SH-2, endoglin | + | (+) | +hi |
| CD146 | ENDO 3 | + | (+)/- | +/- |
| VEGFR2 | +/- | — | ||
| von Willebrand factor | + | (+) | (+) | |
| Integrins, adhesion molecules | ||||
| CD29 | β1 integrin, VLA-β | +hi | +lo | +hi |
| CD43 | Sialophorin | (+) | — | +/- |
| CD44 | H-CAM | +/- | + | + |
| CD47 | Neurophilin | (+) | (+) | + |
| CD49a | α1 integrin, VLA-1 | + | +/- | + |
| CD49b | α2 integrin, VLA-2 | — | — | + |
| CD49c | α3 integrin, VLA-3 | + | +/- | + |
| CD49d | α4 integrin, VLA-4 | — | — | + |
| CD49e | α5 integrin, VLA-5 | (+) | +/- | + |
| CD49f | α6 integrin, VLA-6 | (+) | — | (+) |
| CD51 | αV integrin, VNR-α | (+) | (+) | + |
| CD61 | β3 integrin | — | — | +/- |
| CD104 | β4 integrin | +/- | — | +/- |
| Miscellaneous | ||||
| CD13 | Aminopeptidase N | + | + | + |
| CD34 | + | (+) | —a | |
| CD36 | GPIIIb | +hi | +/- | +/- |
| CD38 | +lo | +/- | — | |
| CD45 | Leucocyte common R | — | — | — |
| CD90 | Thy-1 | + | + | + |
| CD117 | c-KIT, SCFR | — | — | — |
| CD133 | AC133 | — | — | — |
| HLA ABC | + | + | + | |
| HLA DR | + | — | — | |
| NGFR | — | +/- | — |
+, >90% of the cells positive for the marker; (+), <90% but >10% of the cells positive for the marker; +/-, <10% but >2% of the cells positive for the marker; —, <2% of the cells positive for the marker.
a
In one donor, expression of CD34 in cultured cells was (+)