Table 2.
Selected genes overexpressed in freshly isolated CD31- cells compared with freshly isolated CD31+ cells
| Gene name | Fold difference |
|---|---|
| Cell cycle-related genes | |
| Inhibin, beta A (activin A, activin AB alpha polypeptide) | 18 |
| Growth arrest-specific 1 | 11 |
| Growth arrest-specific 7 | 10 |
| Stem cell- and development-related genes | |
| Zinc finger DAZ interacting protein 1 | 40 |
| Slit homolog | 27 |
| Sema domain, immunoglobulain domain, short basic domain, secreted (semaphorin) 3C | 26 |
| Fibroblast activation protein alpha | 21 |
| Mesencymal stem cell protein DSC54 | 12 |
| Wingless-type MMTV integration site family, member 5A | 9 |
| Dickkopf homolog 2 | 6 |
| Frizzled homolog 7 | 5 |
| Cytokine- and cytokine receptor-related genes | |
| Insulin-like growth factor1 (somatomedin C) | 25 |
| Platelet-derived growth factor receptor-like | 25 |
| Chemokine (C-X-C motif) ligand 14 | 23 |
| Insulin-like growth factor binding protein 6 | 13 |
| Insulin receptor substrate 1 | 8 |
| Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 8 |
| Complement system | |
| Complement component 3 | 29 |
| Complement component 1s | 18 |
| Complement component D (adipsin) | 10 |
| Complement component 7 | 10 |
| Adipose tissue-related | |
| Phospholipase A2, group IIA | 21 |
| LR8 protein (VLDL receptor) | 17 |
| Apolipoprotein D | 12 |
| Phospholipase A2, group IVA | 12 |
| Bone-related | |
| Osteoglycin (osteoinducive factor, mimecan) | 22 |
| Osteomodulin | 21 |
| Cathepsin K | 15 |
| Osteonectin/sparc | 14 |
| Decorin | 13 |
| Cartilage- and extracellular matrix-related | |
| Microfibrillar-associated protein 4 | 83 |
| Fibulin 1 | 50 |
| Dermatopontin | 43 |
| EGF-containing fibulin-like extracellular matrix protein 1 | 31 |
| Glypican 3 | 26 |
| Fibulin 5 | 25 |
| Microfibril-associated glycoprotein-2 | 24 |
| Hyaluronan synthase 1 | 22 |
| Matrix metalloproteinase 2 (gelatinase A, 72 kDa) | 14 |
| Cartilage intermediate layer protein | 14 |
| Collagen, type I, alpha 1 | 14 |
| Collagen, type XIV, alpha 1 (undulin) | 13 |
| Collagen, type VI, alpha 2 | 12 |
| Matrix Gla protein | 11 |
| Nervous system-related | |
| Neuro-oncological ventral antigen1 | 28 |
| Doublecortin and CaM kinase like 1 | 17 |
| Glutamate receptor, ionotrophic, AMPA 3 | 15 |
| Myelin basic protein | 10 |
| Muscle-related | |
| Myosin heavy chain polypeptide 11, smooth muscle | 33 |
| Sarcospan | 15 |
| Laminin, alpha 2 | 14 |
| Phospholamban | 13 |
| Other | |
| KIAA0527 protein | 80 |
| Solute carrier family 22 (extraneuronal monoamine transporter), member 3 | 69 |
| Prostaglandin F receptor | 42 |
| WNT1 inducible signaling pathway protein 2 | 39 |
| Integrin, beta-like 1 (with EGF-like repeat domains) | 37 |
| CD44 antigen (H-CAM) | 11 |
The table presents the 30 most highly overexpressed transcripts plus selected transcripts with presumed biological relationship with some of the most highly overexpressed transcripts. In addition, some transcripts with relevance to biology discussed in the text are presented. If a gene was represented with more than one probe in the list, the probe with the highest degree of differential expression was selected. The values represent the median from three donors.