Table 6.
Selected genes up-regulated in cultured ADASC compared with freshly isolated CD31- cells
| Gene name | Fold difference |
|---|---|
| Development-related | |
| Forkhead box (FOX) D1 | 24 |
| Odd Oz/Ten-m homolog 3 | 19 |
| Maternal embryonic leucine zipper kinase | 14 |
| Cysteine knot superfamily 1, BMP antagonist 1 | 13 |
| Dickkopf homolog 1 | 10 |
| Wingless-type MMTV integration site family, member 5A | 4 |
| Signal transduction-, growth- and growth regulatory—related genes | |
| Stanniocalcin 2 | 48 |
| Hepatocyte growth factor receptor | 30 |
| Inhibin, beta A (activin A, activin AB alpha polypeptide) | 21 |
| CDC42 effector protein (Rho GTPase binding) 3 | 15 |
| v-myb myeloblastosis viral oncogene homolog (avian)-like 1 | 13 |
| Cell adhesion—related genes N-cadherin (neuronal) | |
| Activated leukocyte cell adhesion molecule (CD166, ALCAM) | 17 |
| Integrin alpha 4 (CD49d) | 8 |
| Bone-related | |
| Osteoprotegerin | 25 |
| Cartilage- and matrix-related | |
| Cartilage oligomeric matrix protein | 56 |
| Collagen, type XI, alpha 1 | 20 |
| Cartilage-linking protein | 18 |
| Proteoglycan 1, secretory granule | 15 |
| Aggrecan 1 | 11 |
| Fibronectin 1 | 10 |
| Cytoskeleton related—genes | |
| Keratin 7 | 288 |
| Keratin 18 | 22 |
| Desmoplakin | 17 |
| Tropomyosin 2 (beta) | 17 |
| Other | |
| NADPH dehydrogenase, quinone 1 | 75 |
| Solute carrier family 7, member 11 | 31 |
| KIAA1199 protein | 23 |
| Potassium channel, subfamily K, member 2 | 19 |
| A desintegrin and metalloproteinase (ADAM) domain 10 | 19 |
| Asp (abnormal spindle)-like, microcephaly-associated | 17 |
| Tumor protein D52-like 1 | 16 |
| Endoglin (CD105) | 4 |
The table presents the 30 most highly overexpressed transcripts plus selected transcripts with presumed biological relationship with some of the most highly overexpressed transcripts. In addition, some transcripts with relevance to biology discussed in the text are presented. If a gene was represented with more than one probe in the list, the probe with the highest degree of differential expression was selected. The values represent the median from three donors.