Figure 1.

Deferoxamine (DFO) effects on total iron levels in rats with spinal cord injury.

Compared with that in sham-operated rats, the iron level at the injury site is significantly higher 2 days after the damage (**P < 0.01). DFO-treated rats show iron levels markedly lower than those in injured saline-treated rats and similar to those in the sham-operated rats, especially 2 weeks post injury (***P < 0.001). Data are expressed as the mean ± SEM (n = 3 per group, one-way analysis of variance followed by Tukey's post hoc test). DFO: Deferoxamine.