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. 2017 Jun;12(6):959–968. doi: 10.4103/1673-5374.208591

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Copyright: © Neural Regeneration Research

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DFO effects on motor function in rats after spinal cord injury.

All groups exhibit increasing BBB scores over time. The first evaluation was conducted immediately after laminectomy in all groups. No statistically significant differences in BBB scores are initially observed between the injured saline- (Injury) and DFO-treated (Injury + DFO) rats (P > 0.05), whereas the BBB scores in the sham-operated rats were significantly different from both the injured saline- and DFO-treated rats (***P < 0.001). However, beginning at the second evaluation 2 weeks-post injury, the BBB scores for the injured saline- and DFO-treated rats were significantly different from each other (*P < 0.05; mean ± SEM, n = 3 per group, one-way analysis of variance followed by Tukey's post hoc test). DFO: Deferoxamine; BBB: Basso, Beattie, Bresnahan locomotor rating scale.