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. 2017 Jun;12(6):981–986. doi: 10.4103/1673-5374.208594

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Copyright: © Neural Regeneration Research

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Immunofluorescence staining for 5-HT in the trigeminal subnuclei Sp5O (A), Sp5I (B) and NTS (C).

Mild to moderate cTBI altered the expression of 5-HT (red) in Sp5O (–10.84 mm to Bregma), Sp5I (–13.00 mm to Bregma) and NTS (–14.56 mm to Bregma) compared to the corresponding areas of the normal control animals. Scale bar: 50 μm. The position of Bregma was decided according to the rat brain atlas (Paxinos and Watson, 2007). 5-HT: Serotonin; Sp5O: spinal trigeminal nucleus oralis; Sp5I: spinal trigeminal pars interpolaris; NTS: nucleus tractus solitaries; cTBI: closed head traumatic brain injury.