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. 2017 Jun;12(6):981–986. doi: 10.4103/1673-5374.208594

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Copyright: © Neural Regeneration Research

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Immunofluorescence labeling of the trigeminal subnuclei Sp5O (A), Sp5I (B) and NTS (C).

Mild to moderate cTBI altered the immunoreactivity of DβH (green) and the expression of NK1R (red) in Sp5O (–10.88 mm to Bregma), Sp5I (–13.04 mm to Bregma) and NTS (–14.60 mm to Bregma) compared to the corresponding areas of control animals. Scale bar: 50 μm in all figures. The position of Bregma was decided according to the rat brain atlas (Paxinos and Watson, 2007). cTBI: Closed head traumatic brain injury; DβH: dopamine beta hydroxylase; NK1R: neurokinin 1 receptor; Sp5O: spinal trigeminal nucleus oralis; Sp5I: spinal trigeminal pars interpolaris; NTS: nucleus tractus solitaries.