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. 2017 Apr 8;8(23):36984–36995. doi: 10.18632/oncotarget.16974

Figure 1. Zerumbone ameliorated diet-induced adiposity in C57BL/6N mice.

Figure 1

A. Body weight of mice from the NC, HF, HF + LZ, and HF + HZ groups was measured weekly during the experimental period (n = 10). NC, mice fed normal control diet; HF, mice fed high-fat diet; HF+LZ, mice fed high-fat diet containing 0.01% zerumbone; HF+HZ, mice fed high-fat diet containing 0.025% zerumbone. B. Effect of zerumbone on body weight gain after 8 weeks of experimental diet. C. Measurement of food intake during experimental period. D. Effect of zerumbone on epididymal white adipose tissue (WAT) weight. E. Histological staining of WAT. Epididymal adipose tissues were isolated and stained with H&E and examined microscopically. F. Average adipocyte size was quantified in H&E-stained paraffin sections in five mice per group. *P < 0.05 versus HF. G. Aspartate aminotransferase (AST) and H. alanine transaminase (ALT) activity were measured in liver homogenates.