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. 2017 Mar 14;8(23):37080–37090. doi: 10.18632/oncotarget.16180

Table 3. Univariate analysis demonstrating factors associated with OS and PFS in matched patients.

Factor Cases (n) OS p-value HR (95% CI) PFS p-value HR (95% CI)
Treatment regimen 0.796 1.074 (0.624–1.851) 0.630 1.129 (0.688–1.853)
 TP 41
 CS 41
Age 0.168 0.674 (0.385–1.181) 0.116 0.664 (0.399–1.106)
 age < 58 35
 age ≥58 47
Sex 0.428 1.338 (0.652–2.748) 0.498 1.265 (0.641–2.499)
 Female 12
 Male 70
ECOG PS 0.002 2.416 (1.366–4.276) 0.013 1.976 (1.156–3.379)
 0–1 58
 2 24
T Stage 0.000 4.101 (2.269–7.413) 0.000 2.570 (1.546–4.273)
 T3 40
 T4 42
N Stage 0.002 2.387 (1.365–4.172) 0.002 2.304 (1.369–3.876)
 N0 46
 N1 36
M Stage 0.010 2.129 (1.195–3.792) 0.058 1.711 (0.982–2.981)
 M0 58
 M1 24
Clinical Stage 0.000 1.892 (1.321–2.708) 0.009 1.537 (1.111–2.125)
 II 25
 III 33
 IVa 24
Tumor Location 0.173 1.305 (0.890–1.913) 0.082 1.364 (0.061–1.937)
 Upper-third 38
 Middle-third 30
 Lower-third 14
Differentiation 0.255 0.806 (0.556–1.169) 0.327 0.842 (0.597–1.187)
 Well 19
 Fairly 37
 Poorly 26
Tumor Length (cm) 0.252 1.396 (0.789–2.470) 0.082 1611 (0.941–2.758)
 < 5 32
 ≥ 5 50
Weight Loss 0.479 1.233 (0.690–2.203) 0.683 1.119 (0.653–1.919)
 ≤ 10% 57
 > 10% 25
Clinical Response 0.000 3.898 (2.171–6.997) 0.000 3.057 (1.825–5.121)
 CR 41
 Non-CR 41

Abbreviations: n: number of patients; OS: overall survival; PFS: progression-free survival; HR: hazard ratio; CI: confidence interval, CR: complete response.