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. 2017 Mar 15;8(23):37154–37163. doi: 10.18632/oncotarget.16209

Figure 3. Knockdown of YAP inhibits neuroblastoma tumor growth in vivo.

Figure 3

(A) representative macroscopic findings of neuroblastoma tumors. (B, C) tumor volume (n = 4; **P < 0.01), and end-stage tumor weight (n = 4;**P < 0.01) after treatment of SH-SY5Y tumors with Peptide 17 or Control (Ctrl). (D, E) IHC staining of YAP and PCNA expression in SH-SY5Y tumors. The number of YAP and PCNA positive cells and total cells were counted in 5 random fields and analyzed (**P < 0.01). (F) TUNEL assay was performed to detect apoptotic cell in SH-SY5Y tumors. The number of apoptotic cells were counted in 5 random fields and analyzed (**P < 0.01).