Table 3A. Univariate and multivariate Cox proportional hazard regression analysis-between clinicopathologic variables and PFS.
| Variables | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| T status | T1 | 1 | 1 | ||||
| T2 | 1.606 | 1.212–2.127 | 0.001 | 1.610 | 1.206–2.147 | 0.001 | |
| T3 | 2.345 | 1.585–3.469 | 0.000 | 2.076 | 1.339–3.219 | 0.001 | |
| ECE | ECE (−) | 1 | 1 | ||||
| ECE (+) | 1.602 | 1.184–2.167 | 0.002 | 1.372 | 0.978–1.926 | 0.067 | |
| N2 stations | Single | 1 | 1 | ||||
| Multiple | 1.372 | 1.073–1.756 | 0.012 | 1.162 | 0.890–1.518 | 0.270 | |
| Excision | Lobectomy/Tumor resction | 1 | 1 | ||||
| Pneumonectomy | 1.729 | 1.213–2.465 | 0.002 | 1.168 | 1.109–2.330 | 0.012 | |
| LN Skip | LN skip | 1 | 1 | ||||
| status | LN no skip | 1.539 | 1.186–1.997 | 0.001 | 1.618 | 1.216–2.152 | 0.001 |
| Positive | ≤ 25.5% | 1 | 1 | ||||
| LN ratio | > 25.5% | 1.485 | 1.160–1.900 | 0.002 | 1.232 | 0.928–1.636 | 0.148 |