Table 5. PPARG-PPARGC1A-PPARGC1B haplotype frequencies (%) in cases and controls and risk of type 2 diabetes.
| Haplotypes | Cases (n=1004) | Controls (n=1564) | Crude OR (95% CI) | P |
|---|---|---|---|---|
| n (%) | n (%) | |||
| C C T C G G G | 329(33.13) | 507(32.50) | 1.00 | |
| C C C T G G G | 133(13.39) | 244(15.64) | 0.84(0.65-1.08) | 0.176 |
| C C C C G G G | 129(13.00) | 200(12.82) | 0.99(0.77-1.29) | 0.964 |
| C C C C A G G | 98(9.82) | 188(12.05) | 0.80(0.61-1.06) | 0.126 |
| C T T C G G G | 91(9.16) | 101(6.47) | 1.39(1.01-1.90) | 0.041 |
| C T C T G G G | 57(5.74) | 48(3.08) | 1.83(1.22-2.75) | 0.003 |
| C T C C G G G | 32(3.22) | 72(4.62) | 0.68(0.44-1.06) | 0.090 |
| C C T C G C A | 31(3.12) | 32(2.05) | 1.49(0.89-2.49) | 0.124 |
| C T C C A G G | 24(2.42) | 40(2.56) | 0.92(0.55-1.56) | 0.770 |
| G T T C G G G | 15(1.51) | 27(1.73) | 0.86(0.45-1.63) | 0.637 |
| C C C C G C A | 13(1.31) | 16(1.03) | 1.25(0.59-2.64) | 0.553 |
| G T C T G G G | 11(1.11) | 15(0.96) | 1.13(0.51-2.49) | 0.762 |
| C C C C A C A | 0 (0) | 10(0.64) | - | 0.008 |
| Others | 30(3.02) | 60(3.85) | 0.77(.49-1.22) | 0.265 |
With the order of PPARG rs1801282 C>G, PPARG rs3856806 C>T, PPARGC1A rs8192678 C>T, PPARGC1A rs2970847 C>T, PPARGC1A rs3736265 G>A, PPARGC1B rs7732671 G>C and PPARGC1B rs17572019 G>A polymorphisms in gene position. Bold values are statistically significant (P < 0.05).