Table 6. Associations of the PPARGC1A rs3736265 G>A genetic variants with biochemistry characteristics among control participants.
| Genotype | Controls (n=782) | FPG (mmol/L) | P | Total cholesterol (mmol/L) | P | Triglyceride (mmol/L) | P | HDL-C (mmol/L) | P | LDL-C (mmol/L) | P | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | % | |||||||||||
| GG | 557 | 71.41 | 5.16±0.47 | 1.0 | 4.87±1.02 | 1.0 | 1.52±0.93 | 1.0 | 1.29±0.35 | 1.0 | 3.14±0.82 | 1.0 |
| GA | 196 | 25.13 | 5.04±0.50 | 0.002 | 4.88±1.00 | 0.878 | 1.57±0.97 | 0.507 | 1.33±0.39 | 0.238 | 3.11±0.79 | 0.704 |
| AA | 27 | 3.46 | 5.21±0.66 | 0.601 | 5.10±1.22 | 0.249 | 1.97±0.95 | 0.014 | 1.27±0.46 | 0.695 | 3.34±0.92 | 0.220 |
| GA + AA | 223 | 28.59 | 5.06±0.53 | 0.009 | 4.91±1.03 | 0.624 | 1.62±0.97 | 0.179 | 1.32±0.40 | 0.337 | 3.14±0.81 | 0.980 |
| GG+GA | 753 | 96.54 | 5.13±0.48 | 1.0 | 4.87±1.01 | 1.0 | 1.53±0.94 | 1.0 | 1.30±0.36 | 1.0 | 3.13±0.81 | 1.0 |
| AA | 27 | 3.46 | 5.21±0.66 | 0.395 | 5.10±1.22 | 0.249 | 1.97±0.95 | 0.017 | 1.27±0.46 | 0.606 | 3.34±0.92 | 0.197 |
FPG: fasting plasma glucose;
HDL-C, high-density lipoprotein cholesterol;
LDL-C, low-density lipoprotein cholesterol;
Bold values are statistically significant (P <0.05)