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(A) Using immunostainings on metastatic lymph-nodes, p16 score and the percentage of Ki67-expressing cells were significantly higher in women with brain metastases than in women without brain metastases. **p < 0.01, *p < 0.05 (B) There is a correlation between p16 score and the percentage of Ki67-expressing tumor cells (R Pearson coefficient of 0.58, p < 0.01).
