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. 2017 Apr 8;8(23):37409–37422. doi: 10.18632/oncotarget.16964

Figure 3. Repeated valproate-treatment in vivo does not induce expression of CD20 mRNA or surface protein in three CLL patients.

Figure 3

Three CLL patients were treated with valproate (VPA) for three days in three 21-day cycles. For serum levels of valproate, please see Table 3. After 0 and 72 hours of valproate treatment in each cycle, levels of CD20 mRNA (A) and membrane protein (B) were analysed by qPCR and flow cytometry, respectively. Quantibrite beads were used to allow the comparison of the number of CD20 molecules in the plasma membrane between different treatment cycles.