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. 2017 Mar 21;8(23):37448–37463. doi: 10.18632/oncotarget.16394

Figure 6. NT21MP regulates drug resistance via CXCR4.

Figure 6

(A), Quantitative RT-PCR assays were conducted to detect the expression of EMT markers in MDA-MB-231 and PC-MDA-MB-231 cells or in SKBR-3 and CS-SKBR-3 cells with CXCR4 siRNA after 100 ng/mL SDF-1α treatment alone or combined with 1 μg/mL NT21MP. (B), Quantitative RT-PCR assays were conducted to detect the expressions of PDGFA, PDGFB, and PDGFRα for panel A. *P < 0.05, SDF-1α, CXCR4-overexpressing, and si-CXCR4 group vs control; #P < 0.05, NT21MP treatment vs SDF-1α group. (C), Western blotting results for panel B.