Table 2. Association of selected SNPs with plasma levels of MTX at 48 h from the first MTX infusion.
| SNPs | Median (Min-Max) (μmol/L) | P |
|---|---|---|
| SLCO1B1 rs11045879 | 0.287 | |
| CC +TC | 0.50 (0.09–41.63) | |
| TT | 0.39 (0.12–19.88) | |
| SLCO1B1 rs4149056 | 0.441 | |
| TC+TT | 0.45 (0.09–41.63) | |
| CC | 1.1. (0.15–7.53) | |
| SLCO1B1 rs2306283 | 0.294 | |
| CC +TC | 0.45 (0.09–41.63) | |
| TT | 0.37 (0.12–3.91) | |
| SLCO1B1 rs10841753 | 0.017 | |
| TC+TT | 0.47 (0.09–41.63) | |
| CC | 0.32 (0.14–5.50) | |
| SLC19A1 rs1051266 | 0.384 | |
| AA +AG | 0.41 (0.09–34.05) | |
| GG | 0.59 (0.14–41.63) | |
| SLC19A1 rs3788200 | 0.491 | |
| AG+GG | 0.45 (0.09–41.63) | |
| AA | 0.47 (0.11–34.05) | |
| SLC19A1 rs1131596 | 0.219 | |
| TC+CC | 0.41 (0.09–34.05) | |
| TT | 0.6 (0.14–41.63) | |
| SLC19A1 rs2838958 | 0.259 | |
| AG+GG | 0.41 (0.09–34.05) | |
| AA | 0.59 (0.16–41.63) | |
| ABCB1 rs1128503 | 0.149 | |
| TC+CC | 0.47 (0.09–19.88) | |
| TT | 0.39 (0.12–41.63) | |
| ABCB1 rs1045642 | 0.340 | |
| TC+TT | 0.41 (0.12–41.63) | |
| CC | 0.46 (0.09–10.88) | |
| ABCG2 rs2231137 | 0.688 | |
| AG+GG | 0.45 (0.09–41.63) | |
| AA | 0.46 (0.15–10.29) |
SNP: single nucleotide polymorphism.