Table 3. Logistic regression analysis of association between selected SNPs and oral mucositis (grade 3–4).
| SNP (n) | Oral mucositis n (%) | OR (95% CI) | P |
|---|---|---|---|
| SLCO1B1 rs11045879 | |||
| CC (52) | 6 (11.54) | Reference | |
| TC (136) | 18 (13.24) | 1.177 (0.558–2.480) | 0.669 |
| TT (122) | 14 (11.46) | 1.006 (0.364–2.781) | 0.990 |
| TC+TT vs. CC | 0.921 (0.364–2.330) | 0.862 | |
| SLCO1B1 rs4149056 | |||
| CC (6) | 0 | Reference | |
| TC (59) | 5 (8.47) | 0.606 (0.226–1.626) | 0.320 |
| TT (249) | 33 (13.25) | 0 | 0.999 |
| TC+TT vs. CC | 0 | 0.999 | |
| SLCO1B1 rs2306283 | |||
| CC (170) | 23 (13.53) | Reference | |
| TC (115) | 13 (11.30) | 1.643 (0.361–7.478) | 0.521 |
| TT (23) | 2 (8.70) | 1.338 (0.281–6.375) | 0.715 |
| TC+TT vs. CC | 1.283 (0.641–2.566) | 0.481 | |
| SLCO1B1 rs10841753 | |||
| CC (33) | 4 (12.12) | Reference | |
| T C (120) | 17 (14.17) | 1.379 (0.672–2.828) | 0.381 |
| TT (159) | 17 (10.69) | 1.152 (0.361–3.676) | 0.811 |
| TC+TT vs. CC | 0.994 (0.329–3.001) | 0.991 | |
| SLC19A1 rs1051266 | |||
| AA (73) | 7 (9.59) | Reference | |
| A G(142) | 20 (14.08) | 1.252 (0.570–2.749) | 0.576 |
| GG (95) | 11 (11.58) | 0.810 (0.298–2.204) | 0.680 |
| AG+GG vs. AA | 0.705 (0.297–1.675) | 0.428 | |
| SLC19A1 rs3788200 | |||
| AA (73) | 7 (9.59) | Reference | |
| A G(143) | 20 (13.99) | 1.271 (0.579–2.789) | 0.549 |
| GG (97) | 11 (11.34) | 0.829 (0.305–2.255) | 0.714 |
| AG+GG vs. AA | 0.715 (0.301–1.699) | 0.448 | |
| SLC19A1 rs1131596 | |||
| TT (101) | 11 (10.89) | Reference | |
| T C(144) | 20 (13.89) | 1.117 (0.411–3.039) | 0.828 |
| CC (71) | 7 (9.86) | 1.475 (0.592–3.671) | 0.404 |
| TC+CC vs. TT | 0.851 (0.404–1.792) | 0.671 | |
| SLC19A1 rs2838958 | |||
| AA (89) | 10 (11.24) | Reference | |
| AG (145) | 19 (13.10) | 0.970 (0.373–2.526) | 0.951 |
| GG (78) | 9 (11.54) | 1.156 (0.496–2.693) | 0.737 |
| AG+GG vs. AA | 0.882 (0.409–1.900) | 0.748 | |
| ABCB1 rs1128503 | |||
| TT (153) | 13 (8.50) | Reference | |
| T C(121) | 18 (14.88) | 1.882 (0.882–4.014) | 0.102 |
| CC (38) | 7 (18.42) | 2.432 (0.897–6.596) | 0.081 |
| TC+CC vs. TT | 2.009 (0.987–4.090) | 0.054 | |
| ABCB1 rs1045642 | |||
| CC (118) | 14 (11.86) | Reference | |
| T C(148) | 18 (12.16) | 0.965 (0.348–2.676) | 0.945 |
| TT (49) | 6 (12.24) | 0.992 (0.370–2.660) | 0.988 |
| TC+TT vs. CC | 0.970 (0.481–1.959) | 0.933 | |
| ABCG2 rs2231137 | |||
| AA (30) | 5 (16.67) | Reference | |
| AG (123) | 13 (10.57) | 0.821 (0.391–1.724) | 0.603 |
| GG (159) | 20 (12.58) | 1.390 (0.478–4.406) | 0.546 |
| AG+GG vs. AA | 1.509 (0.54104.212) | 0.432 |
SNP: single nucleotide polymorphism; OR: odds ratio; CI: confidential interval.