Table 1. Demographic and baseline characteristics of the patients.
All (N = 261) | TACE (N = 197) | Sorafenib (N = 64) | P | |
---|---|---|---|---|
Age | 56 (20–83)* | 58(20–84)* | 54 (20–79)* | 0.103 |
Sex (N) | 0.094 | |||
Male | 241 | 185 | 56 | |
Female | 20 | 12 | 8 | |
BMI (kg/m2) | 24(15–32)* | 24 (15–32)* | 23 (16–33)* | 0.840 |
Cause of disease (N) | 1.000 | |||
HBV | 195 | 147 | 48 | |
HCV | 4 | 3 | 1 | |
Negative | 62 | 47 | 15 | |
Child–Pugh class (N) | 0.231 | |||
A | 180 | 132 | 48 | |
B | 81 | 65 | 16 | |
BCLC (N) | ||||
AB | 62 | 13 | 0.081 | |
B | 75 | 26 | ||
C | 60 | 25 | ||
Vascular invasion | 0.114 | |||
No | 176 | 138 | 38 | |
Yes | 85 | 59 | 26 | |
Cirrhosis | 0.984 | |||
Yes | 196 | 148 | 48 | |
No | 65 | 49 | 16 | |
MD (mm) | 75 (42–187)* | 74 (42–187)* | 77 (48–175)* | 0.821 |
Lesion number (N) | 0.446 | |||
N = 1 | 113 | 93 | 20 | |
N = 2 | 67 | 33 | 34 | |
N = 3 | 13 | 3 | 10 | |
N ≥ 4 | 68 | 68 | 0 | |
Albumin (g/L) | 35 (21–48)* | 35 (22–44)* | 34 (21–48)* | 0.568 |
TBIL (μmol/L) | 20 (5–52)* | 20 (8–52)* | 22 (5–37)* | 0.812 |
Prothrombin time | 14 (12–16)* | 14 (12–15)* | 14 (12–16)* | 0.418 |
ALT (μmol/L) | 38 (10–566)* | 38 (15–566)* | 39 (10–236)* | 0.480 |
AFP (N) | 0.125 | |||
< 25μg/mL | 69 | 57 | 12 | |
25–400 μg/mL | 93 | 71 | 22 | |
> 400 μg/mL | 99 | 69 | 30 |
Abbreviations:* median (range) for data without normal distribution.
BCLC: Barcelona Clinic Liver Cancer; BMI: body mass index; HBV: hepatitis B virus; HCV: hepatitis C virus; MD: maximum diameter; TBIL: total bilirubin; ALT: alanine aminotransferase, AFP: alpha fetoprotein.