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. 2016 Nov 29;8(23):37855–37865. doi: 10.18632/oncotarget.13675

Table 2. Multivariate cox regression for TTP and OS in all patients.

Cox model* Factors HR (95% CI) P
TTP
Gabor filter 0 Subgroups TACE+sorafenib 0.002
Gabor-1-90 ≤3.6190 0.802 (0.505–1.274)
Gabor-1-90 > 3.6190 2.184 (1.190–4.007)
Gabor filter 1. 0 Subgroups TACE+sorafenib 0.004
Gabor-1-135 ≤1.3995 0.455 (0.231–0.898)
Gabor-1-135 > 1.3995 1.298 (0.827–2.036)
Gabor filter 1.5 Subgroups TACE+sorafenib 0.008
Gabor-1-135 ≤0.5175 0.665 (0.390–1.137)
Gabor-1-135 > 0.5175 1.503 (0.930–2.431)
Wavelet Transform filter 1.0 Subgroups TACE+sorafenib 0.007
Wavelet-2-D ≤18.3585 0.663 (0.393–1.118)
Wavelet-2-D > 18.3585 1.486 (0.912–2.422)
Wavelet Transform filter 1.5 None identified
OS
Wavelet Transform filter 1.0 Subgroups TACE+sorafenib 0.005
Wavelet-3-D < 12.2620 0.759 (0.465–1.239)
Wavelet-3-D > 12.2620 2.115 (1.101–4.062)

Abbreviations:*Seven separate multivariate cox regression analyses were performed: 6 for TTP and 1 for OS, and only variables with a statistical significance were listed.

TTP: time to progression; OS: Overall survival; TACE: transcatheter arterial chemoembolization; HR: hazard ratio; BCLC: Barcelona Clinic Liver Cancer; VI/EM: vascular invasion or extrahepatic metastasis.