Table 1C. List of urinary and serological proteomic biomarkers discovered in prostate cancer in a South African cohort.
| Potential PCa Proteomic biomarkers | Method used | Biospecimen used | Prevalidated | Ethnic trend |
|---|---|---|---|---|
| Prostate-specific antigen | MS | Urine | Y | N |
| Prostatic acid phosphatase;PAPf39 | MS | Urine | Y | N |
| proteasome inhibitor P131 subunit | MS | Urine | N | Y |
| Protein S100-A9 | MS | Urine | N | N |
| Ribonuclease pancreatic | MS | Urine | N | N |
| Roundabout homolog 4 | MS | Urine | N | N |
| Saposin-D | MS | Urine | N | N |
| Serum paraoxonase/arylesterase 1 | MS | Urine | N | N |
| SH3 domain-binding glutamic acid-rich-like protein 3 | MS | Urine | N | N |
| SLAIN motif-containing protein 1 | MS | Urine | Y | Y |
| Tenascin | MS | Urine | N | N |
| Trefoil factor 1 | MS | Urine | N | N |
| Trefoil factor 2 | MS | Urine | N | N |
| Trefoil factor 3 | MS | Urine | N | N |
| Uteroglobin | MS | Urine | N | N |
| Vitamin K-dependent protein S | MS | Urine | Y | N |
| WAP four-disulfide core domain protein 2 | MS | Urine | N | N |
| BORIS BO | CAA | Blood | N | N |
| CAMEL | CAA | Blood | N | N |
| CAML1 | CAA | Blood | N | Y |
| CCDC33 | CAA | Blood | N | N |
| CDK2 | CAA | Blood | N | Y |
| CEACAM1 Isoform 1 | CAA | Blood | N | N |
| COL6A1 | CAA | Blood | N | Y |
| CSAG2 | CAA | Blood | N | N |
| CT47.11 | CAA | Blood | N | N |
| DDX53 | CAA | Blood | N | N |
| DPPA4 | CAA | Blood | N | N |
| EGFR | CAA | Blood | N | N |
| FES | CAA | Blood | N | N |
| FGFR2 | CAA | Blood | N | N |
| GAGE1 | CAA | Blood | N | N |
| GAGE5 | CAA | Blood | N | N |
| LDHC | CAA | Blood | N | N |