Table 6. . Twenty-seven miRNAs associated with the cytokine mixture (p < 0.05).
| miRNA | Samples with miRNA detected n (%) | β-value (95% CI) | p-value | FDR q-value |
|---|---|---|---|---|
| miR-494 |
56 (100) |
-0.48 (-0.68 to -0.29) |
1.3 × 10-6 |
5.7 × 10-5 |
| miR-142-3p |
55 (98) |
0.60 (0.34–0.86) |
6.6 × 10-6 |
0.0001 |
| miR-223-3p |
55 (98) |
0.65 (0.36–0.93) |
7.6 × 10-6 |
0.0001 |
| miR-720† |
56 (100) |
-0.39 (-0.56 to -0.21) |
1.2 × 10-5 |
0.0001 |
| miR-15a-5p |
52 (93) |
0.55 (0.29–0.80) |
2.3 × 10-5 |
0.0001 |
| miR-25-3p |
56 (100) |
0.22 (0.10–0.34) |
0.0005 |
0.003 |
| miR-23a-3p |
53 (95) |
0.35 (0.15–0.55) |
0.0005 |
0.003 |
| miR-4454 |
56 (100) |
-0.44 (-0.71 to -0.16) |
0.002 |
0.008 |
| miR-93-5p |
51 (91) |
0.52 (0.19–0.85) |
0.002 |
0.008 |
| miR-193b-3p |
48 (86) |
-0.63 (-1.03 to -0.23) |
0.002 |
0.008 |
| miR-15b-5p |
52 (93) |
0.41 (0.14–0.67) |
0.003 |
0.009 |
| miR-16-5p |
56 (100) |
0.46 (0.16–0.76) |
0.003 |
0.009 |
| miR-21-5p |
46 (82) |
0.47 (0.16–0.79) |
0.003 |
0.009 |
| miR-30e-5p |
49 (88) |
0.36 (0.12–0.61) |
0.003 |
0.009 |
| miR-29b-3p |
51 (91) |
0.42 (0.14–0.7) |
0.003 |
0.009 |
| miR-1234 |
47 (84) |
-0.35 (-0.60 to -0.10) |
0.005 |
0.01 |
| miR-514b-5p |
56 (100) |
-0.12 (-0.20 to -0.03) |
0.006 |
0.02 |
| miR-19b-3p |
42 (75) |
0.44 (0.11–0.77) |
0.009 |
0.02 |
| miR-125b-5p |
51 (91) |
-0.21 (-0.37 to -0.05) |
0.009 |
0.02 |
| miR-222-3p |
56 (100) |
0.10 (0.03–0.18) |
0.009 |
0.02 |
| miR-148a-3p |
48 (86) |
0.46 (0.08–0.84) |
0.02 |
0.04 |
| miR-374a-5p |
45 (80) |
0.45 (0.08–0.82) |
0.02 |
0.04 |
| miR-191-5p |
55 (98) |
0.35 (0.05–0.66) |
0.02 |
0.04 |
| miR-29a-3p |
53 (95) |
0.34 (0.04–0.65) |
0.03 |
0.05 |
| miR-148b-3p |
34 (61) |
0.24 (0.02–0.45) |
0.03 |
0.05 |
| miR-548aa |
44 (79) |
-0.38 (-0.74 to -0.03) |
0.03 |
0.05 |
| let-7g-5p |
53 (95) |
0.30 (0.02–0.58) |
0.03 |
0.05 |
| miR-1277-3p | 36 (64) | -0.22 (-0.43 to -0.01) | 0.04 | 0.06 |
†miR-720 is no longer annotated as a miRNA.
FDR: False discovery rate.