Table 2. Overlap of genes correlating with turnover before and after removal of immune system-associated cells and tissues (monocytes, bone marrow and spleen).
| Gene | Description | Correlation with cell turnover | Function(s) |
|---|---|---|---|
| BCL10 | B-cell CLL/lymphoma 10 | Negative | Apoptosis |
| BRCA2 | Breast cancer 2, early onset | Negative | Cell cycle |
| CCDC92 | Coiled-coil domain containing 92/limkain beta-2 | Positive | — |
| CCNB2 | Cyclin B2 | Negative | Cell cycle |
| CDC42 | Cell division cycle 42 | Negative | Cell cycle |
| CDCA3 | Cell division cycle associated 3 | Negative | Cell cycle |
| CDCA8 | Cell division cycle associated 8 | Negative | Cell cycle |
| CENPW | Centromere protein W | Negative | Cell cycle |
| CHEK1 | Checkpoint kinase 1 | Negative | Cell cycle |
| CHEK2 | Checkpoint kinase 2 | Negative | Cell cycle |
| CRELD1 | Cysteine-rich with EGF-like domains 1 | Positive | Putative cell adhesion molecule |
| CRY2 | Cryptochrome circadian clock 2 | Positive | Core circadian clock gene |
| DDB2 | Damage-specific DNA binding protein 2, 48 kDa | Negative | DNA repair |
| EXO1 | Exonuclease 1 | Negative | DNA repair |
| FANCD2 | Fanconi anemia, complementation group D2 | Negative | Cell cycle |
| FOXM1 | Forkhead box M1 | Negative | Cell cycle |
| HEY1 | Hes-related family bHLH transcription factor with YRPW motif 1 | Positive | Transcription factor |
| HNRNPF | Heterogeneous nuclear ribonucleoprotein F | Negative | mRNA stability and transport |
| KIF11 | Kinesin family member 11 | Negative | Cell cycle |
| KIF23 | Kinesin family member 23 | Negative | Cell cycle |
| MKI67 | Marker of proliferation Ki-67 | Negative | Cell cycle |
| MSH5 | mutS homolog 5 | Negative | DNA repair |
| NADSYN1 | NAD synthetase 1 | Negative | Redox reaction coenzyme, precursor for cell signaling molecules, and substrate for protein post-translational modifications |
| NCAPG | Non-SMC condensin I complex, subunit G | Negative | Cell cycle |
| NCAPH | Non-SMC condensin I complex, subunit H | Negative | Cell cycle |
| NUF2 | NUF2, NDC80 kinetochore complex component | Negative | Cell cycle |
| ORC1 | Origin recognition complex, subunit 1 | Negative | Cell cycle |
| PARPBP | PARP1 binding protein | Negative | Cell cycle |
| PLK4 | Polo-like kinase 4 | Negative | Cell cycle |
| RCC1 | Regulator of chromosome condensation 1 | Negative | Cell cycle |
| SAMD9 | Sterile alpha motif domain containing 9 | Negative | Apoptosis |
| SNRPN | Small nuclear ribonucleoprotein polypeptide N | Positive | Complex SNURF-SNRPN locus: mRNA processing, short non-coding RNA precursor |
| STK26 | Serine/threonine protein kinase 26 | Negative | Apoptosis |
| STK38 | Serine/threonine kinase 38 | Negative | Cell cycle and apoptosis |
| TP53 | Tumor protein p53 | Negative | Apoptosis |
| ZWINT | ZW10 interacting kinetochore protein | Negative | Cell cycle |
Abbreviation: mRNA, messenger RNA.