Table 1.
Characteristics of all children who initiated ART at Dora Nginza Hospital in Port Elizabeth, South Africa by transfer status (N = 1,582)
| All |
Ever transferred |
Never transferred |
||
|---|---|---|---|---|
| N (%) | N (%) | N (%) | p-Value | |
| 1,582 (100.0) | 901 (57.0) | 681 (43.0) | ||
| Year of ART initiation | ||||
| 2004–2006 | 381 (24.2) | 292 (32.5) | 89 (13.1) | <.0001 |
| 2007–2009 | 579 (36.7) | 420 (46.7) | 159 (23.5) | |
| 2010–2012 | 416 (26.4) | 154 (17.1) | 262 (38.6) | |
| 2013–2015 | 201 (12.8) | 33 (3.7) | 168 (24.8) | |
| Age at ART Initiation, median (IQR) | 4 (1–8) | 4 (1–8) | 3 (1–8) | 0.06 |
| <2 | 480 (30.3) | 229 (25.4) | 251 (36.9) | |
| 2–5 | 488 (30.9) | 308 (34.2) | 180 (26.4) | <.0001 |
| 6–10 | 490 (31.0) | 307 (34.1) | 183 (26.9) | |
| >10 | 124 (7.8) | 57 (6.3) | 67 (9.8) | |
| Female | 755 (47.7) | 425 (47.2) | 330 (48.5) | 0.64 |
| CD4 cell/mm3 at ART initiation, median (IQR) | 278 (119–526) | 276 (131–507) | 285 (99–545) | 0.32 |
| <200 | 223 (36.6) | 130 (35.0) | 93 (39.1) | 0.31 |
| 200–350 | 145 (23.8) | 98 (26.3) | 47 (19.8) | |
| 351–500 | 83 (13.6) | 49 (13.2) | 34 (14.3) | |
| >500 | 159 (26.1) | 95 (25.5) | 64 (26.9) | |
| Missing CD4 at ART initiation | 972 (61.4) | 529 (58.7) | 443 (65.1) | 0.01 |
| ART initiation regimen by age | ||||
| <3 years | ||||
| ABC+3TC+EFV | 10 (1.6) | 3 (1.0) | 7 (2.2) | <.0001 |
| ABC+3TC+LPV/r | 236 (37.4) | 65 (20.5) | 171 (54.5) | |
| d4T+3TC+EFV | 34 (5.4) | 23 (7.3) | 11 (3.5) | |
| d4T+3TC+LPV/r | 287 (45.5) | 194 (61.2) | 93 (29.6) | |
| Other | 64 (10.1) | 32 (10.1) | 32 (10.2) | |
| ≥3 years | ||||
| ABC+3TC+EFV | 281 (30.1) | 86 (15.0) | 195 (54.0) | <.0001 |
| ABC+3TC+LPV/r | 25 (2.7) | 10 (1.7) | 15 (4.2) | |
| d4T+3TC+EFV | 465 (49.7) | 362 (63.1) | 103 (28.5) | |
| d4T+3TC+LPV/r | 22 (2.4) | 14 (2.4) | 8 (2.2) | |
| Other | 142 (15.2) | 102 (17.8) | 40 (11.1) | |
| Last viral load copies/mL at DNH, median (IQR) | ||||
| >1 million | 13 (1.2) | 5 (0.9) | 8 (1.5) | 0.01 |
| 10,000–999,999 | 136 (12.5) | 53 (9.4) | 83 (15.9) | |
| 1,000–9,999 | 61 (5.6) | 37 (6.6) | 24 (4.6) | |
| 400–999 | 37 (3.4) | 17 (3.0) | 20 (3.8) | |
| <400 | 838 (77.2) | 450 (80.1) | 388 (74.2) | |
| Missing viral load | 497 (31.4) | 339 (37.6) | 158 (23.2) | <.0001 |