Table 2.
Characteristics of children transferred after ART initiation at Dora Nginza Hospital in Port Elizabeth, South Africa to 16 health facilities in the Eastern Cape Province of South Africa (N = 644)
| All |
Successful transfer |
LTF during transfer |
||
|---|---|---|---|---|
| N (%) | N (%) | N (%) | p-Value | |
| 644 (100.0) | 433 (67.2) | 211 (32.7) | ||
| Year of ART initiation | ||||
| 2004–2006 | 231 (35.9) | 158 (36.6) | 73 (34.6) | 0.60 |
| 2007–2009 | 314 (48.8) | 207 (47.9) | 107 (50.7) | |
| 2010–2012 | 85 (13.2) | 60 (13.9) | 25 (11.9) | |
| 2013–2015 | 13 (2.0) | 7 (1.6) | 6 (2.8) | |
| Age at ART Initiation, median (IQR) | 4 (2–8) | 4 (2–8) | 4 (1–8) | 0.14 |
| <2 | 154 (23.9) | 92 (21.3) | 62 (29.4) | 0.05 |
| 2–5 | 220 (34.2) | 153 (35.3) | 67 (31.8) | |
| 6–10 | 229 (35.6) | 164 (37.9) | 65 (30.8) | |
| >10 | 41 (6.4) | 24 (5.5) | 17 (8.1) | |
| Year of transfer | ||||
| 2004–2006 | 1 (0.2) | 0 (0) | 1 (0.5) | 0.55 |
| 2007–2009 | 67 (10.4) | 45 (10.4) | 22 (10.4) | |
| 2010–2012 | 541 (84.0) | 365 (84.3) | 176 (83.4) | |
| 2013–2015 | 35 (5.4) | 23 (5.3) | 12 (5.7) | |
| Age at transfer, median (IQR) | 8 (5–11) | 8 (5–11) | 7 (4–11) | 0.08 |
| <2 | 30 (4.7) | 18 (4.2) | 12 (5.7) | 0.05 |
| 2–5 | 185 (28.7) | 111 (25.6) | 74 (35.1) | |
| 6–10 | 230 (35.7) | 165 (38.1) | 65 (30.8) | |
| >10 | 199 (30.9) | 139 (32.1) | 60 (28.4) | |
| Median months from ART to transfer (IQR) | 37.3 (20.6–50.6) | 38.3 (20.7–51.2) | 36.2 (19.3–50.0) | 0.41 |
| Female | 312 (48.5) | 210 (48.5) | 102 (48.3) | 0.97 |
| CD4 at ART initiation, median (IQR) | 271 (128–494) | 276 (120–521) | 262.5 (141–434) | 0.35 |
| <200 | 95 (34.6) | 67 (35.5) | 28 (32.6) | 0.31 |
| 200–350 | 76 (27.6) | 46 (24.3) | 30 (34.9) | |
| 351–500 | 38 (13.8) | 27 (14.3) | 11 (12.8) | |
| >500 | 66 (24.0) | 49 (25.9) | 17 (19.8) | |
| Missing CD4 at ART initiation | 369 (57.3) | 244 (56.4) | 125 (59.2) | 0.49 |
| ART initiation regimen by age | ||||
| <3 years at ART | 0.97 | |||
| ABC+3TC+EFV | 3 (1.4) | 2 (1.5) | 1 (1.2) | |
| ABC+3TC+LPV/r | 34 (15.5) | 22 (16.7) | 12 (13.8) | |
| d4T+3TC+EFV | 18 (8.2) | 10 (7.6) | 8 (9.2) | |
| d4T+3TC+LPV/r | 141 (64.4) | 84 (63.6) | 57 (65.5) | |
| Other | 23 (10.5) | 14 (10.6) | 9 (10.3) | |
| ≥3 years at ART | 0.68 | |||
| ABC+3TC+EFV | 43 (10.3) | 31 (10.5) | 12 (9.8) | |
| ABC+3TC+LPV/r | 6 (1.4) | 3 (1.0) | 3 (2.4) | |
| d4T+3TC+EFV | 280 (66.8) | 202 (68.2) | 78 (63.4) | |
| d4T+3TC+LPV/r | 13 (3.1) | 9 (3.0) | 4 (3.3) | |
| Other | 77 (18.4) | 51 (17.2) | 26 (21.1) | |
| Last viral load copies/mL at DNH, median (IQR) | ||||
| >1 million | 2 (0.6) | 0 (0) | 2 (1.8) | 0.15 |
| 10,000–999,999 | 25 (7.3) | 18 (7.8) | 7 (6.3) | |
| 1,000–9,999 | 26 (7.6) | 17 (7.3) | 9 (8.1) | |
| 400–999 | 10 (2.9) | 9 (3.9) | 1 (0.9) | |
| <400 | 280 (81.6) | 188 (81.0) | 92 (82.9) | |
| Missing viral load | 301 (46.7) | 201 (46.4) | 100 (47.4) | 0.82 |