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Agreement between CFR, FFR and iFR. When CFR is below 2, 23% of patients may have normal FFR (>0.80) and the agreement between CFR and iFR is much better than that of CFR and FFR. Such scenario may be common in acute coronary syndromes with low CFR. CFR, coronary flow reserve; CFVR, coronary flow velocity reserve; FFR, fractional flow reserve; iFR, instantaneous wave-free ratio. (Adapted from Tomai et al).38
