Table 4. Multiple comparisons between each of two subgroups of UM patients.

Markers1	A		B		C		D		E		F
MW (Da)	1467		1207.56		1741.61		2024.2		4054.88		4117.41
Normal mean	455.61		232.38		12.00		12.77		34.13		33.17
Mean intensity of UM I	87.8		67.3		43.4		32.6		87.1		61
Mean intensity of UM II	45.4		46.4		36.5		30.5		113.1		72.6
Mean intensity of UM III	433		178.4		17		14.4		29.7		30.1
F value	33.775		27.529		13.919		6.052		24.934		27.615
P value	<0.001		<0.001		<0.001		0.007		<0.001		<0.001
P value of I vs II	0.419		0.284		0.199		0.721		0.04		0.059
P value of II vs III	<0.001		<0.001		0.001		0.009		<0.001		<0.001
P value of I vs III	<0.001		<0.001		<0.001		0.004		<0.001		<0.001
Marker1	H	I		J		K		L		M		N
MW (Da)	4964.57	1351.66		1897.62		3263.52		1264.62		1520.56		3192.67
Normal mean	25.8	81.6		17.6		296.9		66.2		30.8		160.9
Mean intensity of UM I	75.3	29.6		77		161.4		28		18.3		82.6
Mean intensity of UM II	70	17.5		62.6		161		23.5		16.2		92.2
Mean intensity of UM III	20.1	94.9		24.1		243		69.1		31.1		126.6
F value	10.994	14.718		7.001		7.901		20.113		14.897		5.821
P value	<0.001	<0.001		0.006		0.002		<0.001		<0.001		0.008
P value of I vs II	0.682	0.436		0.337		0.988		0.573		0.484		0.488
P value of II vs III	0.001	<0.001		0.017		0.002		<0.001		<0.001		0.017
P value of I vs III	<0.001	<0.001		0.002		0.002		<0.001		<0.001		0.003

UM I, II and III mean refer to the three subgroups of UM patients at three different time points respectively. I: Pre-operative; II: Post-operative 1mo; III: Post-operative 6mo. F value corresponds to the fixed factor of the grouping in univariate analysis of variance. P value below 0.05 was regarded as significant. The following three P values were generated by multiple comparisons between each of two subgroups of UM patients and were regarded as significant if <0.05. ¹Peptide peaks of marker G (MW 4173.61 Da) was not detected in sera of UM II patients and multiple camparisons were not performed.