Figure 3. Effect of fluorofenidone on VEGF expression in murine retinas.
VEGF expression was statistically upregulated in retinas of db/db mice, which was suppressed by fluorofenidone treatment. The difference between placebo-treated db/db mice and db/db mice treated with fluorofenidone was statistically significant (aP<0.05). The difference between placebo-treated db/db mice and normal control mice was statistically significant (cP<0.05).