Table 2.
Predictors of persistent acute kidney injury
| Univariate OR (95% CI) | p Value | Multivariable OR* (95% CI) | p Value | |
| Age/10-year increase | 0.77 (0.59 to 1.00) | 0.052 | 0.85 (0.63 to 1.16) | 0.312 |
| eGFR/10 mL/min/1.73 m2 increase | 0.99 (0.98 to 1.00) | 0.179 | 0.88 (0.79 to 0.98) | 0.019 |
| Contrast volume per 10 mL increase | 1.03 (1.00 to 1.05) | 0.028 | 1.02 (1.00 to 1.05) | 0.052 |
| Male | 2.55 (1.61 to 4.04) | <0.001 | 2.68 (1.63 to 4.38) | <0.001 |
| Known diabetes | 1.30 (0.81 to 2.09) | 0.280 | 1.09 (0.66 to 1.80) | 0.735 |
| LVEF | ||||
| >50% | 1.0 (ref) | 1.0 (ref) | ||
| 40%–49% | 1.25 (0.72 to 2.19) | 0.418 | 1.02 (0.57 to 1.81) | 0.955 |
| 30%–39% | 1.59 (0.91 to 2.78) | 0.104 | 1.18 (0.66 to 2.12) | 0.580 |
| <30% | 1.01 (0.45 to 2.28) | 0.964 | 0.74 (0.32 to 1.72) | 0.489 |
| Logistic EuroSCORE I (n=1332) | 1.88 (0.42 to 8.51) | 0.407 | – | – |
| Prosthesis make | Ref (CoreValve) | – | – | |
| Edwards | 0.96 (0.63 to 1.47) | 0.856 | – | – |
| Other | 0.21 (0.03 to 1.53) | 0.119 | – | |
| COPD | 1.84 (1.17 to 2.91) | 0.009 | 1.59 (0.99 to 2.59) | 0.057 |
| Bleeding complication | 1.40 (0.51 to 2.78) | 0.978 | 1.64 (0.81 to 3.33) | 0.169 |
| Access site | 1.0 (ref: transfemoral) | 1.0 (ref: transfemoral) | ||
| Apical | 2.30 (1.47 to 3.79) | <0.001 | 2.23 (1.35 to 3.69) | 0.002 |
| Subclavian | 1.31 (0.31 to 5.63) | 0.713 | 1.34 (0.30 to 5.94) | 0.697 |
| Direct aortic | 3.17 (0.91 to 11.1) | 0.070 | 3.54 (0.95 to 13.3) | 0.060 |
| Prior CABG/PCI | 1.26 (0.83 to 1.92) | 0.278 | 0.90 (0.57 to 1.42) | 0.658 |
The following interaction terms were tested: gender and contrast volume to creatinine clearance ratio: p value 0.321; gender and age: p value 0.770; gender and diabetes: p value 0.995; gender and access site: p value 0.465.
*The multivariable model was adjusted for age, sex, LVEF, baseline eGFR, contrast volume, COPD, diabetes, known hypertension, prior coronary revascularisation, bleeding complication and procedural access site.
CABG, coronary artery bypass graft; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; LVEF, left ventricular ejection fraction; PCI, percutaneous coronary intervention.