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Kaplan–Meier curves showing the survival of breast cancer patients when they initially have no evidence of metastasis to when they progress through their metastatic disease. (a) Comparison of ER+/HER2−, ER−/HER2−, and HER2+ patients, (b) patients with a solitary first metastatic site at bone, chest wall, liver, or brain, and (c) subsets of patients with different numbers of first relapse metastases.
