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. 2015 Jun 17;1:15007. doi: 10.1038/npjbiofilms.2015.7

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Copyright © 2015 Nanyang Technological University/Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Criteria for defining keystone nodes in microbial species interaction and community-wide metabolic networks. (a) Criteria for identifying keystone species in reconstructed species interaction networks. Nodes represent taxa and edges represent associations between them. Node sizes reflect activity. (b) Criteria for identifying genes encoding key functionalities in reconstructed community-wide metabolic networks. Nodes represent enzyme-coding genes and edges correspond to shared metabolites (either reactants, products or educts). Node sizes reflect relative expression.