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. Author manuscript; available in PMC: 2018 Jun 21.
Published in final edited form as: Bioconjug Chem. 2017 May 18;28(6):1767–1776. doi: 10.1021/acs.bioconjchem.7b00237

Figure 2. OVCAR8 ovarian cancer model.

Figure 2

(A) Mice injected IP with 2e6 OVCAR8.ffluc cells developed widespread metastatic disease in the abdomen. (B) Tumor progression over 4 weeks observed in n=3 mice/time point. Micrometastases are observed by week 1. Macrometastases are first seen at week 2, and increase in number, size and distribution over time. Data represents average number of macroscopic metastases +/− SEM. (C) Organ pluck at 3 weeks showing ovarian metastases (small white nodules; red arrows) on liver, pancreas and intestinal surfaces.