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NSC/SiNP[Pt] given IP enhance the retention of Pt at tumor sites. At 1, 2, 6 and 24 hours, tumors from NSC/SiNP[Pt]-treated animals had higher levels of Pt than those treated with free cisplatin or drug-loaded NPs. Statistical significance was determined using a two-tailed students t-test (* p <0.05, ** p<0.01, *** p<0.001).
