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. Author manuscript; available in PMC: 2018 Jun 15.
Published in final edited form as: Eur J Pharmacol. 2017 Mar 18;805:25–35. doi: 10.1016/j.ejphar.2017.03.034

Fig. 4. CM16 cellular penetration and distribution in the ER and protein synthesis inhibitio.

Fig. 4

A: CM16 fluorescence properties allow its visualization in blue color (filter ex/em: 359–371/397 nm) in Hs683 cells over time after 5 μM treatment. B: CM16 parallel distribution to the endoplasmic reticulum fluorescent probe (ER-tracker) after a 3 h treatment in Hs683, C: SKMEL-28 and D: MDA-MB-231 cell lines. Exposure times for blue filter (ex/em) 359–371/397 nm: 40 ms (SKMEL-28) and 80 ms (Hs683 and MDA-MB-231); and for red filter (ex/em) 540–580/593–668 nm: 283 ms (SKMEL-28) and 850 ms (Hs683 and MDA-MB-231). All pictures were taken with a 40× objective. Illustrations are representative of one experiment performed in two replicates.