Table 1.
Number of exons and chromosomal localization of the 78 orthologous D. melanogaster, D pseudoobscura and A. gambiae OXPHOS genes
| Cluster ID* | Protein name | D. melanogaster gene name | Number of exons† | Map position | FlyBase ID | D. pseudoobscura gene name | Number of exons† | Map position | A. gambiae gene name | Number of exons† | Map position |
| Complex I: NADH:ubiquinone oxidoreductase | |||||||||||
| NUMM | 13 kDa A subunit | CG8680 | 3 | 2L;25C6 | FBgn0031684 | Dpse\CG8680 | 3 | 4 | agEG14117 | 3 | 3R;33B |
| NUFM | 13 kDa B subunit | CG6463 | 3 | 3L;67E7 | FBgn0036100 | Dpse\CG6463 | 3 | XR | agEG15380 | 3 | 2L22E |
| NIPM | 15 kDa subunit | CG11455 | 2 | 2L;21B1-2 | FBgn0031228 | Dpse\CG11455 | 2 | 4 | agEG13302 | 2 | 3R;35C-D |
| NUYM | 18 kDa subunit | CG12203 | 3 | X;18C7 | FBgn0031021 | Dpse\CG12203 | 3 | XL | agEG18985 | 4 | 2L;27A |
| NUPM | 19 kDa subunit | CG3683 | 4 | 2R;60D13 | FBgn0035046 | Dpse\CG3683 | 4 | 3 | agEG19249 | 3 | 2L;26B |
| NUKM | 20 kDa subunit | CG9172 | 1 | X; 14A5 | FBgn0030718 | Dpse\CG9172 | 1 | ND | agEG16939 | 1 | X;4A |
| NUIM | 23 kDa subunit | ND23 | 3 | 3R;89A5 | FBgn0017567 | Dpse\CG3944 | 3 | 2 | agEG9698 | 2 | 2R;9A |
| NUHM | 24 kDa subunit | CG5703 | 3 | X; 16B10 | FBgn0030853 | Dpse\CG5703 | 3 | XL | agEG16953 | 5 | 2R;11A |
| NUGM | 30 kDa subunit | CG12079 | 3 | 3L;63B7 | FBgn0035404 | Dpse\CG12079 | 3 | XR | agEG11610 | 3 | 2L;24D |
| NUEM | 39 kDa subunit | CG6020 | 4 | 3L;77C6 | FBgn0037001 | Dpse\CG6020 | 4 | XR | agEG18760 | 3 | 3L;40A |
| NUDM | 42 kDa subunit | ND42 | 2 | 3R;94A1 | FBgn0019957 | Dpse\CG6343 | 2 | 2 | agEG10090 | 2 | 3L;41C |
| NUCM | 49 kDa subunit | CG1970 | 6 | 4;102C2 | FBgn0039909 | Dpse\CG1970 | 6 | ND | agEG18856 | 1 | X;1B |
| NUBM | 51 kDa subunit | CG9140 | 4 | 2L;26B6-7 | FBgn0031771 | Dpse\CG9140 | 4 | 4 | agEG9927 | 4 | 3R;36D |
| NUAM | 75 kDa subunit | ND75 | 5 | X;7E1 | FBgn0017566 | Dpse\CG2286 | 5 | XL | agEG19681 | 4 | 2R;8D |
| NI8M | B8 subunit | CG15434 | 3 | 2L;24F3 | FBgn0040705 | Dpse\CG15434 | 3 | 4 | agEG16251 | 3 | 2R;15B |
| NB2M | B12 subunit | CG10320 | 2 | 2R;57F6 | FBgn0034645 | Dpse\CG10320 | 2 | 3 | agEG9277 | 1 | 3L;46D |
| NB4M | B14 subunit | CG7712 | 3 | 2R;47C6 | FBgn0033570 | Dpse\CG7712 | 3 | 3 | agEG12033 | 2 | 2R;15A |
| N4AM | B14.5A subunit | CG3621 | 2 | X; 2D6-E1 | FBgn0025839 | Dpse\CG3621 | 2 | XL | agEG14707 | 4 | 2R;17A |
| N4BM | B14.5B subunit | CG12400 | 3 | 2L:23D3 | FBgn0031505 | Dpse\CG12400 | 3 | 4 | agEG16232 | 3 | 2R;13C |
| NB5M | B15 subunit | CG12859 | 2 | 2R;51C2 | FBgn0033961 | Dpse\CG12859 | 2 | 3 | agEG17759 | 2 | 3L;44C |
| NB6M | B16.6 subunit | CG3446 | 2 | X;5F2 | FBgn0029868 | Dpse\CG3446 | 2 | XL | agEG7829 | 3 | 3R;35A |
| NB7M | B17 subunit | l(2)35Di | 3 | 2L;35D | FBgn0001989 | Dpse\CG13240 | 3 | 4 | agEG18567 | 3 | 3R;34D |
| N7BM | B17.2 subunit | CG3214 | 4 | 2L;23A1 | FBgn0031436 | Dpse\CG3214 | 4 | 4 | agEG10758 | 4 | 3R;31A |
| NB8M | B18 subunit | CG5548 | 1 | X;13A8 | FBgn0030605 | Dpse\CG5548 | 1 | XL | agEG8436 | 3 | 2L;28C |
| NI2M | B22 subunit | CG9306 | 3 | 2L;34B8 | FBgn0032511 | Dpse\CG9306 | 3 | 4 | agEG12344 | 3 | 3R;35C-D |
| ACPM | Acyl carrier | mtacp1 | 4 | 3L;61F6 | FBgn0011361 | Dpse\CG9190 | 4 | XR | agEG11237 | 5 | 3L;38B |
| NIAM | ASHI subunit | CG3192 | 3 | X;6C5 | FBgn0029888 | Dpse\CG3192 | 3 | XL | agEG8821 | 3 | 2R;10A |
| NUML | MLRQ subunit | CG32230 | 3 | 3L;80E2 | FBgn0052230 | Dpse\CG32230 | 3 | XR | agEG12063 | 3 | 2R;15A |
| NINM | MNLL subunit | CG18624 | 1 | X;7C | FBgn0029971 | Dpse\CG18624 | 1 | XL | agEG22692 | 1 | X;5A |
| NIDM | PDSW subunit | Pdsw | 3 | 2L;23F3 | FBgn0021967 | Dpse\CG8844 | 3 | 4 | agEG7887 | 4 | 3R;29A |
| NISM | SGDH subunit | l(3)neo18 | 4 | 3L;68F5 | FBgn0011455 | Dpse\CG9762 | 4 | XR | agEG13573 | 2 | 2L;27D |
| NIGM | AGGG subunit | CG40002 | 3 | ND | FBgn0058002 | Dpse\CG40002 | 3 | XR | agEG18653 | 2R;12D | |
| Complex II: Succinate dehydrogenase | |||||||||||
| DHSA | Flavoprotein subunit | Scs-fp | 4 | 2R;56D3 | FBgn0017539 | Dpse\CG17246 | 4 | 3 | agEG7754 | 3 | 3L;38B |
| DHSB | Iron-sulfur protein | SdhB | 3 | 2R;42D3-4 | FBgn0014028 | Dpse\CG3283 | 3 | 3 | agEG13539 | 4 | 2L;27D |
| C560 | Cytochrome B560 subunit | CG6666 | 2 | 3R;86D7-8 | FBgn0037873 | Dpse\CG6666 | 2 | 2 | agEG14929 | 2 | 3L;39B |
| DHSD | Cytochrome b small subunit | CG10219 | 4 | 3R;95B1 | Fbgn0039112 | Dpse\CG10219 | 4 | XR | agEG16772 | 3 | X;1C |
| Complex III: Ubiquinol-cytochrome c reductase | |||||||||||
| UCRY | 6.4 kDa protein | CG14482 | 2 | 2R;54C9 | FBgn0034245 | Dpse\CG14482 | 2 | 3 | agEG12505 | 2 | 3L;43B |
| UCRX | 7.2 kDa protein | ox | 2 | 2R;49C2 | FBgn0011227 | Dpse\CG8764 | 2 | 3 | agEG15210 | 2 | 2L;20C |
| UCRH | 11 kDa protein | Ucrh | 2 | 3R | FBgn0066066 | Dpse\Ucrh | 2 | 2 | agEG19398 | 2 | 2R;11B |
| UCR6 | 14 kDa protein | CG3560 | 3 | X;14B10 | FBgn0030733 | Dpse\CG3560 | 3 | XL | agEG11611 | 3 | 3L;46A |
| UCRI | Iron-sulfur subunit | RFeSP | 3 | 2L;22A3 | FBgn0021906 | Dpse\CG7361 | 3 | 4 | agEG16975 | 4 | 3R;32C |
| CY1 | Cytochrome c1, heme protein | CG4769 | 6 | 3L;64C13 | FBgn0035600 | Dpse\CG4769 | 6 | XR | agEG19223 | 4 | 2L;26C |
| UCR1 | Core protein 1 | CG3731 | 6 | 3R;88D6 | FBgn0038271 | Dpse\CG3731 | 6 | 2 | agEG21302 | 3 | X;5C |
| UCR2 | Core protein 2 | CG4169 | 4 | 3L;73A10 | FBgn0036642 | Dpse\CG4169_1 | 4 | XR | agEG17930 | 4 | 2L;24A |
| UCRQ | Ubiquinone-binding protein QP- | CG7580 | 2 | 3L;74C3 | FBgn0036728 | Dpse\CG7580 | 2 | XR | agEG20223 | 2 | 3L;38C |
| Complex IV: Cytochrome c oxidase | |||||||||||
| CX41 | Polypeptide IV | CG10664 | 2 | 2L;38A8 | FBgn0032833 | Dpse\CG10664 | 2 | 4 | agEG13327 | 2 | 3R;31C |
| COXA | Polypeptide Va | CoVa | 1 | 3R;86F9 | FBgn0019624 | Dpse\CG14724 | 1 | 2 | agEG19581 | 1 | 3L;41D |
| COXB | Polypeptide Vb | CG11015 | 3 | 2L;26E3 | FBgn0031830 | Dpse\CG11015 | 3 | 4 | agEG8633 | 4 | 3R;31C |
| COXD | Polypeptide VIa | CG17280 | 2 | 2R;59E3 | FBgn0034877 | Dpse\CG17280 | 2 | 3 | agEG7821 | 2 | X;5A |
| COXG | Polypeptide VIb | CG18809 | 1 | X;18E5 | FBgn0042132 | Dpse\CG18809 | 1 | XL | agEG11043 | 1 | 2L;25A |
| COXH | Polypeptide VIc | cype | 2 | 2L;25D6 | FBgn0015031 | Dpse\CG14028 | 2 | 4 | EST357342 | 2 | 3R;29A |
| COXK | Polypeptide VIIa | CG9603 | 2 | 3R;84F13 | FBgn0040529 | Dpse\CG9603 | 2 | XR | agEG17423 | 3 | X;4B |
| COXO | Polypeptide VIIc | CG2249 | 2 | 2R;46D8-9 | FBgn0040773 | Dpse\CG2249 | 2 | 3 | agEG22887 | 2 | 2L;28C |
| Complex V: ATP synthase | |||||||||||
| ATPA | Alpha chain | blw | 4 | 2R;59B1-2 | FBgn0011211 | Dpse\CG3612 | 4 | 3 | agEG7500 | 4 | 2L;21E |
| ATPB | Beta chain | ATPsyn-beta | 3 | 4;102D1 | FBgn0010217 | Dpse\CG11154 | 3 | ND | agEG14379 | 1 | 3L;45C |
| ATPG | Gamma chain | ATPsyn-gamma | 1 | 3R;99B10 | FBgn0020235 | Dpse\CG7610 | 1 | 2 | agEG7678 | 2 | 3R;29C |
| ATPD | Delta chain | CG2968 | 3 | X;9B4 | FBgn0030184 | Dpse\CG2968 | 3 | ND | agEG16076 | 1 | 3R;29B |
| ATPE | Epsilon chain | sun | 4 | X;13F12 | FBgn0014391 | Dpse\CG9032 | 4 | ND | agEG10095 | 4 | X;3D |
| ATPF | B chain | ATPsyn-b | 3 | 3L;67C5 | FBgn0019644 | Dpse\CG8189 | 3 | XR | agEG9580 | 3 | 2R;7A |
| ATPQ | D chain | ATPsyn-d | 1 | 3R;91F | FBgn0016120 | Dpse\CG6030 | 1 | ND | agEG10180 | 3 | 3L;41C |
| ATPJ | E chain | CG3321 | 1 | 3R;88B4 | FBgn0038224 | Dpse\CG3321 | 1 | 2 | agEG10809 | 3 | 2L;26B |
| ATPK | F chain | CG4692 | 2 | 2R;60D8-9 | FBgn0035032 | Dpse\CG4692 | 2 | 3 | agEG1544 | 1 | ND |
| ATPN | G chain | l(2)06225 | 2 | 2L;32C1 | FBgn0010612 | Dpse\CG6105 | 2 | ND | agEG8590 | 2 | 3R;34B |
| ATPR | Coupling factor 6 | ATPsyn-Cf6 | 2 | 3R;94E13 | FBgn0016119 | Dpse\CG4412 | 2 | 2 | agEG19097 | 2 | 2R;19D |
| AT91 | Lipid-binding protein P1 | CG1746 | 3 | 3R;100B7 | FBgn0039830 | Dpse\CG1746 | 3 | 2 | agEG14837 | 3 | X;2B |
| ATPO | OSCP | Oscp | 3 | 3R;88E8-9 | FBgn0016691 | Dpse\CG4307 | 3 | 2 | agEG9393 | 3 | 2R;15D |
| Others | |||||||||||
| ATPW | ATP synthase coupling factor B | CG10731 | 1 | 2R;52F | FBgn0034081 | Dpse\CG10731 | 1 | 3 | agEG15185 | 1 | 2R;19B |
| CI30 | Complex I intermediate- associate protein 30 | CG7598 | 2 | 3R;99B9 | FBgn0039689 | Dpse\CG7598 | 2 | 2 | agEG7818 | 2 | X;5A |
| CYC | Cytochrome C | Cyt-c-p | 1 | 2L;36A11 | FBgn0000409 | Dpse\CG17903 | 1 | 4 | agEG17602 | 1 | 3R;34C |
| COXZ | Complex IV assembly protein COX11 | CG6922 | 1 | 2L;25E5 | FBgn0031712 | Dpse\CG6922 | 1 | 4 | agEG19985 | 2 | 3L;38B |
| COXS | Complex IV copper chaperone | CG9065 | 2 | X;13A9 | FBgn0030610 | Dpse\CG9065_1 | 2 | XL | agEG23169 | 1 | 3L;44C |
| OXA1 | Biogenesis protein OXA1 | CG6404 | 3 | 3L;67F1 | FBgn0027615 | Dpse\CG6404 | 3 | XR | agEG11581 | 3 | 2L;22C |
| ETFA | Electron transfer flavoprotein alpha subunit | wal | 3 | 2R;48C1-2 | FBgn0010516 | Dpse\CG8996 | 3 | 3 | agEG11798 | 2 | 2R;17B |
| ETFB | Electron transfer flavoprotein beta subunit | CG7834 | 2 | 3R;99C1 | FBgn0039697 | Dpse\CG7834 | 2 | 2 | agEG13614 | 2 | 2R;19D |
| ETFD | Electron transfer flavoprotein- ubiquinone oxidoreductase | CG12140 | 5 | 2R;46C4 | FBgn0033465 | Dpse\CG12140 | 5 | 3 | agEG10998 | 4 | 2L;23B |
| COXX | Protoheme IX farnesyltransferase | CG5037 | 4 | 2L;31D9 | FBgn0032222 | Dpse\CG5037 | 3 | ND | agEG11452 | 4 | 3R;32B |
| SCO1 | Sco1 protein homolog | CG8885 | 2 | 2L;25B5 | FBgn0031656 | Dpse\CG8885 | 2 | 4 | agEG10475 | 1 | 3R;31C |
| SUR1 | Surfeit locus protein 1 | Surf1 | 4 | 3L65D4 | FBgn0029117 | Dpse\CG9943 | 4 | XR | agEG8998 | 4 | 2L;25C |
*IDs in this column are taken from Swiss-Prot [20]. †Only coding exons were considered. ND, map position not determined. D. melanogaster, D. pseudoobscura and A. gambiae sequences used to determine intron-exon gene structures are available as supplementary material at the MitoComp website [22]