Table 16:

Disutilities Used in the Economic Model

Health State	Disutility	Standard Deviation	Duration	Source
Treatment-Related Disutilities
LAAC device implantation	0.060	0.0012	One-time	Garg et al, 200867
Aspirin	0.002	0.0004	Ongoing	Gage et al, 199665
Apixaban	0.006	0.0012	Ongoing	O'Brien et al, 200566
Dabigatran	0.006	0.0012	Ongoing	O'Brien et al, 200566
Rivaroxaban	0.006	0.0012	Ongoing	O'Brien et al, 200566
Warfarin	0.013	0.0026	Ongoing	Gage et al, 199665
Event-Related Disutilities
Device embolization	0.250	0.0558	One-time	Saw et al, 201636
Pericardial effusion	0.159	0.0318	One-time	Saw et al, 201636
Major bleed	0.159	0.172	One-time	Thomson et al, 200068
Minor bleed	0.011	0.011	One-time	Thomson et al, 200068
Systemic embolism	0.279	0.0558	One-time	Sullivan et al, 200569

Abbreviation: LAAC device, left atrial appendage closure device with delivery system.