Table 20:

Scenario Analysis 2—Parameter Inputs for Procedural and Nonprocedural Events

	Estimate	Standard Error	Source
Base Case
Event	OR, LAAC device:warfarin
Ischemic stroke	1.56	0.3569	Holmes et al, 201420; Reddy et al, 201440
Major bleed	0.95	0.2011	Holmes et al, 201420; Reddy et al, 201440
Scenario
Event	Probability of procedural event
Ischemic stroke	1.25	0.2239	Holmes et al, 201420; Reddy et al, 201440
Major bleed	0.55	0.1908	FDA, 201555
	Nonprocedural OR, LAAC device:warfarin
Ischemic stroke	0.008	0.0033	Holmes et al, 201420; Reddy et al, 201440
Major bleed	0.055	0.0084	FDA, 201555

Abbreviations: LAAC device, left atrial appendage closure device with delivery system; OR, odds ratio.