Table 14:
GRADE Evidence Profile for Robot-Assisted Versus Open Radical Prostatectomy for Health-Related Quality of Life
| # Studies (Design) | Risk of Bias | Inconsistency | Indirectness | Imprecision | Publication Bias | Upgrade Considerations | Quality |
|---|---|---|---|---|---|---|---|
| 1 RCT | No serious limitations | No serious limitations | No serious limitations | Serious limitations (−1)a | Undetected | None | ⊕⊕⊕ Moderate |
| 2 non-RCTs | Serious limitations (−1)b | No serious limitations | No serious limitations | Serious limitations (−1)a | Undetected | None | ⊕ Very low |
Abbreviations: GRADE, Grading of Recommendations Assessment, Development, and Evaluation; RCT, randomized controlled trial.
a
Not powered to detect differences.
b
Nonrandomized studies start at low GRADE. Differences in baseline patient characteristics between groups may impact recovery and thus health-related quality of life scores.