Table 16:
GRADE Evidence Profile for Robot-Assisted Versus Open Radical Prostatectomy for Time to Mobilization or Return to Work or Activity
| # Studies (Design) | Risk of Bias | Inconsistency | Indirectness | Imprecision | Publication Bias | Upgrade Considerations | Quality |
|---|---|---|---|---|---|---|---|
| 1 RCT | No serious limitations | No serious limitations | No serious limitations | Serious limitations (−1)a | Undetected | None | ⊕⊕⊕ Moderate |
| 3 non-RCTs | Serious limitations (−1)b | Serious limitations (−1)c | No serious limitations | Serious limitations (−1)a | Undetected | None | ⊕ Very low |
Abbreviations: GRADE, Grading of Recommendations Assessment, Development, and Evaluation; RCT, randomized controlled trial.
a
Not powered to detect differences. No standardized method for measurement.
b
Nonrandomized studies start at low GRADE. Differences in baseline patient characteristics between robot-assisted and open prostatectomy groups may impact time to mobilization or return to work or activity.
c
One study found a significant difference favouring robot-assisted radical prostatectomy for time to mobilization.