Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 May 18;2:16014. doi: 10.1038/npjbcancer.2016.14

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Breast Cancer Research Foundation/Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Hot-spot field selection by different laboratories on the same core-cut biopsy slide. (a) Selections (indicated by red circles) on some example core biopsies. (b) Example of a single-core biopsy (median score: 12%) with zoomed-in fields. Each laboratory was asked to circle the area considered by that laboratory to be the hot-spot (b-i). Most pathologists honed in on the same area of the core, although individual-selected circular scoring fields do not always overlap. (b-iii, b-iv) Segments of the same area chosen by two different laboratories to read Ki67. (b-v) The ‘outlier’ field selected by only one laboratory as the hot-spot.